Almost every language in the world has always been trying to enrich their dictionary. Therefore, the development of every language is reflected in its word treasure. The semantical and grammatical structure of lexis, its general and specific features, origin and current use are studied in lexicology. The literal meaning of the term lexicology is ‘the study of the word’ (made of by joining two ancient Greek words: lexis – ‘word, phrase’ and logos – ‘learning, knowledge’ [3, 7]). Words are lexically and semantically related to each other in different ways. The term that is used to describe this concept is lexical relationship. The common types of lexical relationships are: synonymy, antonymy, homonymy and polysemy. In this article, homonyms are investigated in the base of English and Uzbek languages to distinguish their certain similarities and disparate features.