HISTORY OF THE STUDY ABOUT GASTRODUODENAL ULCERS

The earliest evidence of gastroduodenal peptic ulcers was the mummy of a 60-year-old Chinese man who died in 163 BC. The remains were perfectly preserved and it was obvious that death was the result of peritonitis, the cause of which was a perforated ulcer of the prepyloric part of the stomach. Some clinical manifestations of stomach and duodenal ulcers were known in ancient times. They were pointed out in their treatises by Hippocrates, Celsius, and Galen. They associated the disease with disorders of the nervous system and recommended various options for a gentle diet as the main treatment. Avicenna in the “Canon of Medical Science” described in detail the syndrome, the main characteristic of which was hunger pain and night pain that went away after eating. In the 18th century, Morgagni described in some detail the clinical picture of duodenal ulcer. In 1816, F.K. Houdin, in his work “Academic Readings on Chronic Diseases,” described in more detail the picture of stomach ulcers. These individual descriptions end the first empirical period in the history of the study of gastric and duodenal ulcers.